Effect of exposure to an extremely low frequency-electromagnetic field on the cellular collagen with respect to signaling pathways in osteoblast-like cells.

@article{Soda2008EffectOE,
  title={Effect of exposure to an extremely low frequency-electromagnetic field on the cellular collagen with respect to signaling pathways in osteoblast-like cells.},
  author={Akira Soda and Toshitaka Ikehara and Yohsuke Kinouchi and Kazuo Yoshizaki},
  journal={The journal of medical investigation : JMI},
  year={2008},
  volume={55 3-4},
  pages={
          267-78
        }
}
The effect of exposure to extremely low frequency-electromagnetic field (ELF-EMF: 3 mT, 60 Hz) on differentiation of mouse osteoblast-like MC3T3-E1 cells was examined together with addition of insulin-like growth factor I (IGF-I). As a marker of the differentiation, the cellular collagen content was determined by the absorbance of Sirius red-stained cells measured at the wavelength of 510-520 nm with an imaging microspectroscopy. Exposure to ELF-EMF increased significantly the collagen in the… CONTINUE READING