Effect of exposure of rabbit hepatocytes to sulfur-containing anthelmintics (oxfendazole and fenbendazole) on cytochrome P4501A1 expression.

Abstract

The expression of cytochrome P4501A1 and 1A2 was investigated in rabbit hepatocytes maintained in primary cultures for 96 hr in the absence or presence of 100 mum of the benzimidazole anthelmintics oxfendazole or fenbendazole. Total cytochrome P-450, ethoxyresorufin O-deethylase and acetanilide hydroxylase activities were significantly increased in cell… (More)

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@article{GleizesEscala1996EffectOE, title={Effect of exposure of rabbit hepatocytes to sulfur-containing anthelmintics (oxfendazole and fenbendazole) on cytochrome P4501A1 expression.}, author={C Gleizes-Escala and P Lesca and G. Larrieu and Jacques Dupuy and Thierry Pineau and Pierre Galtier}, journal={Toxicology in vitro : an international journal published in association with BIBRA}, year={1996}, volume={10 2}, pages={129-39} }