Effect of experimentally induced Escherichia coli epididymo-orchitis and ciprofloxacin treatment on rat spermatogenesis

@article{Demir2007EffectOE,
  title={Effect of experimentally induced Escherichia coli epididymo-orchitis and ciprofloxacin treatment on rat spermatogenesis},
  author={Aslan Demir and Polat T{\"u}rker and Fikret Fatih Onol and Serap Şirvanci and Ayfer Findik and Tufan Tarcan},
  journal={International journal of urology : official journal of the Japanese Urological Association},
  year={2007},
  volume={14 3},
  pages={268-72}
}
We investigated the effects of epididymo-orchitis and ciprofloxacin on rat testicular histology and spermatogenesis. The control group underwent left orchiectomy. The second group received oral ciprofloxacin (150 mg/kg/day) for 10 days. Escherichia coli (10(6) cfu/mL, 0.1 mL) was injected into the proximal right ductus deferens in the third group. The fourth group received ciprofloxacin treatment 48 h after E. coli inoculation. In groups 3 and 4, bilateral orchiectomy was performed 14 days… CONTINUE READING

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