Effect of experimental hyperhomocysteinemia on cardiac structure and function in the rat.

Abstract

Male Sprague-Dawley rats were subjected for 2 weeks to daily injections of homocysteine (Hcy), which increased plasma Hcy approximately 2-fold. Echocardiography indicated significant increases in left ventricular diastolic (13%) and systolic (31%) dimensions and decreases in posterior wall thickness (diastolic, -17%; systolic, -20%) in Hcy-treated animals… (More)

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@article{Walker2004EffectOE, title={Effect of experimental hyperhomocysteinemia on cardiac structure and function in the rat.}, author={Ernest M. Walker and Jason Black and C. J. Parris and Elizabeth C Bryda and Silvestre Cansino and Lisa Hunt and Jean Chappell and Paulette S Wehner and Mark Studeny and Gary L. Wright}, journal={Annals of clinical and laboratory science}, year={2004}, volume={34 2}, pages={175-80} }