Effect of experimental diabetes on the susceptibility of myelin proteins to proteolysis.

@article{Spritz1981EffectOE,
  title={Effect of experimental diabetes on the susceptibility of myelin proteins to proteolysis.},
  author={Norton Spritz and Harmeet Singh and Barbara Marinan and I Silberlicht},
  journal={Diabetes},
  year={1981},
  volume={30 4},
  pages={292-5}
}
To investigate abnormalities in peripheral nerve myelin in experimental diabetes, we studied the effects of the proteolytic enzymes trypsin and alpha-chymotrypsin on the proteins of this membrane, obtained from the sciatic nerves of normal rats and from animals made diabetic with streptozotocin. The dominant effect of the proteolytic enzymes was to… CONTINUE READING