Effect of exogenous melatonin on vascular reactivity and nitric oxide in postmenopausal women: role of hormone replacement therapy.

@article{Cagnacci2001EffectOE,
  title={Effect of exogenous melatonin on vascular reactivity and nitric oxide in postmenopausal women: role of hormone replacement therapy.},
  author={Angelo Cagnacci and Serenella Arangino and Marco Angiolucci and Gian Benedetto Melis and Fabio Facchinetti and Stefania Malmusi and Annibale Volpe},
  journal={Clinical endocrinology},
  year={2001},
  volume={54 2},
  pages={261-6}
}
OBJECTIVE Several effects of melatonin are modulated by gonadal steroids and are reduced in ageing women. Administration of melatonin reduces internal carotid artery pulsatility index (PI), and blood pressure in young individuals. Whether these effects are conserved in postmenopausal women and are influenced by hormone replacement therapy (HRT), was herein investigated. DESIGN Randomised, double-blind placebo controlled study. PATIENTS Twenty-three postmenopausal women of which 11 were… CONTINUE READING
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