Effect of exogenous bovine growth hormone and ovariectomy on prepubertal mammary growth, serum hormones and acute in-vitro proliferative response of mammary explants from Holstein heifers.

@article{Purup1993EffectOE,
  title={Effect of exogenous bovine growth hormone and ovariectomy on prepubertal mammary growth, serum hormones and acute in-vitro proliferative response of mammary explants from Holstein heifers.},
  author={Stig Purup and Kris Sejrsen and John Foldager and Robert Michael Akers},
  journal={The Journal of endocrinology},
  year={1993},
  volume={139 1},
  pages={
          19-26
        }
}
Sixteen prepubertal Holstein Friesian heifers were used to study the effect of long-term administration of bovine GH (bGH) on mammary development in intact and ovariectomized heifers. Eight heifers were ovariectomized at 2.5 months of age. Four intact and four ovariectomized heifers received subcutaneous injection of bGH (15 mg/day) for 15 weeks starting at 176 +/- 3 days of age (147 +/- 3 kg body weight), while the remaining eight heifers received an equal volume of excipient. Blood samples… CONTINUE READING

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