Effect of exenatide on beta cell function after islet transplantation in type 1 diabetes.

@article{Ghofaili2007EffectOE,
  title={Effect of exenatide on beta cell function after islet transplantation in type 1 diabetes.},
  author={Khalid Al Ghofaili and Michelle Fung and Ziliang Ao and Mark Meloche and Robert J. Shapiro and Garth L. Warnock and Dariush Elahi and Graydon S Meneilly and D. Michael Thompson},
  journal={Transplantation},
  year={2007},
  volume={83 1},
  pages={
          24-8
        }
}
BACKGROUND Islet transplantation can reduce or eliminate the need for insulin in patients with type 1 diabetes. Exenatide is a long acting analogue of Glucagon-like peptide-1 (GLP-1) that augments glucose induced insulin secretion, and may increase beta cell mass. We evaluated the effect of exenatide on insulin secretion after islet transplantation. METHODS Eleven C-peptide positive islet cell recipients with elevated glucose levels were treated with exenatide for three months. Response was… CONTINUE READING

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