Effect of ethylene glycol on the interaction of different myosin subfragment 1.nucleotide complexes with actin.

@article{Mushtaq1989EffectOE,
  title={Effect of ethylene glycol on the interaction of different myosin subfragment 1.nucleotide complexes with actin.},
  author={E Mushtaq and Lois E. Greene},
  journal={Biochemistry},
  year={1989},
  volume={28 15},
  pages={6478-82}
}
To elucidate the structure of the cross-bridge intermediates in the actomyosin ATPase cycle, several laboratories have added both ethylene glycol and AMP-PNP to muscle fibers. These studies suggested that ethylene glycol shifts the structure of myosin.AMP-PNP toward the weak-binding conformation, i.e., toward the structure of myosin.ATP. Since only the weak-binding conformation of myosin subfragment 1 (S-1) binds with no apparent cooperativity to the troponin-tropomyosin-actin complex… CONTINUE READING

From This Paper

Topics from this paper.
3 Citations
0 References
Similar Papers