• Corpus ID: 42597526

Effect of ethanolic extract of Hibiscus rosa sinensis L., flowers on hair growth in female wistar rats

@inproceedings{Upadhyay2011EffectOE,
  title={Effect of ethanolic extract of Hibiscus rosa sinensis L., flowers on hair growth in female wistar rats},
  author={Sukirti Upadhyay and Prashant Upadhyay and Ashoke Kumar Ghosh and Vijayender Singh and Vinod Kumar Dixit},
  year={2011}
}

• S. Upadhyay, P. Upadhyay, +2 authors V. Dixit
• Published 2011

Hibiscus rosasinensis flower is known as hair growt h promoter in traditional and folklore medicines. Petroleum ether extract of H.rosasinensis is report ed in literature for hair growth promotion. The stu dy was aimed to investigate the efficacy of ethanolic extract of H.rosa sinensis flower as hair growth promoter. Female wistar rats were selected for hai growth promotion studies. They were divided in three groups and their skin was denuded with hair r emoving cream, electronic shavers and hair clippers for ensuring complete removal of hair. Then 2% solu ti ns of vehicle (control), minoxidil (standard) an d ethanolic extract of H.rosa sinensis flowers respec tiv ly were applied on shaved denuded skin of diffe rent groups of rats twice a day for thirty days. During this period they were observed visually for pattern of hair growth studies and after treatment period thei r skin biopiosis were taken for follicular density and cyclic phases of hair growth. On the basis of visua l observation of animals and histopathology, ethano lic extract of H.rosasinensis flowers showed shorter ha ir and take more time for growth and favours telogenic stage of hair follicles as compared to co ntr l thus it showed hair growth retarding activity inspite of hair growth promoting one. Which is also of use in retarding body hair growth for beautification in females. This study proved that e thanolic extract of H.rosa sinensis flowesr may hav e potential as hair growth retarding agent so it may use in preparations for hair removing creams . Key WordsHair, H. rosa sinensis , minoxidil, wistar rats, ethanolic. _________________________________________________________________________