Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial.

@article{Rapp2003EffectOE,
  title={Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial.},
  author={Stephen R. Rapp and Mark A. Espeland and Sally A. Shumaker and Victor W. Henderson and Robert L. Brunner and Joann E. Manson and Margery L. S. Gass and Marcia L. Stefanick and Dorothy S Lane and J. K. Hays and Karen C Johnson and Laura H. Coker and Maggie Dailey and D. R. Bowen},
  journal={JAMA},
  year={2003},
  volume={289 20},
  pages={2663-72}
}
CONTEXT Observational studies have suggested that postmenopausal hormone treatment may improve cognitive function, but data from randomized clinical trials have been sparse and inconclusive. The Women's Health Initiative Memory Study (WHIMS) is an ancillary study of the Women's Health Initiative (WHI) hormone therapy trials. On July 8, 2002, the estrogen plus progestin therapy in the WHI trial was discontinued because of certain increased health risks for women. OBJECTIVE To determine whether… CONTINUE READING
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