Effect of estrogen on flow-induced dilation in NO deficiency: role of prostaglandins and EDHF.

@article{Huang2001EffectOE,
  title={Effect of estrogen on flow-induced dilation in NO deficiency: role of prostaglandins and EDHF.},
  author={Aliaksandr Huang and Yubo Beth Wu and Dong Hua Sun and Akos Koller and Gabor Kaley},
  journal={Journal of applied physiology},
  year={2001},
  volume={91 6},
  pages={
          2561-6
        }
}
To investigate the role of estrogen in flow-induced dilation (FiD) in nitric oxide (NO) deficiency, FiD was examined in isolated gracilis arterioles of ovariectomized (OVX) and OVX rats with estrogen replacement (OVE). Both groups of rats were treated chronically with N(omega)-nitro-L-arginine methyl ester. Plasma concentration of NO(2)/NO(3) was reduced in both groups. Plasma concentration of estradiol was lower in OVX than in OVE rats. FiD was similar in vessels of the two groups; calculated… CONTINUE READING
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