Effect of estrogen on cellular metabolism of the human anterior cruciate ligament.

@article{Yu1999EffectOE,
  title={Effect of estrogen on cellular metabolism of the human anterior cruciate ligament.},
  author={Wendy Yu and Shubing Liu and Joshua D Hatch and Vah{\'e} R Panossian and Gerald A. M. Finerman},
  journal={Clinical orthopaedics and related research},
  year={1999},
  volume={366},
  pages={229-38}
}
Previous studies from this laboratory have established the presence of estrogen receptors in the human anterior cruciate ligament. The purpose of this study was to investigate the effects of 17 beta-estradiol on cell proliferation and procollagen levels, as an indicator of collagen synthesis, in the human anterior cruciate ligament fibroblasts. Fibroblast proliferation and procollagen synthesis in response to near log concentrations of 17 beta-estradiol (at 0.0029 ng/mL, 0.025 ng/mL, 0.25 ng/mL… CONTINUE READING

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