Effect of erythropoietin on oxygen-induced brain injury in the newborn rat.

@article{Yi2008EffectOE,
  title={Effect of erythropoietin on oxygen-induced brain injury in the newborn rat.},
  author={Uluç Yiş and Semra Hiz Kurul and Abdullah Kumral and Kazim Tuğyan and Serap Cilaker and Osman Fatih Yilmaz and Şermin Genç and K{\"u}rşat Genç},
  journal={Neuroscience letters},
  year={2008},
  volume={448 3},
  pages={245-9}
}
The developing nervous system is sensitive to supraphysiological oxygen concentrations. Recent studies showed that exposure to hyperoxia in infant rats leads to extensive apoptotic degeneration in the cortex and white matter of the developing brain. A wide variety of experimental studies have shown that erythropoietin exerts a remarkable neuroprotection in… CONTINUE READING