Effect of erythrocyte ingestion on macrophage antibacterial function.

  title={Effect of erythrocyte ingestion on macrophage antibacterial function.},
  author={William L. Hand and N L King-Thompson},
  journal={Infection and immunity},
  volume={40 3},
Individuals with sickle cell anemia are subject to serious infections caused by a number of bacteria, including Salmonella species and Staphylococcus aureus. It has been suggested that in sickle cell anemia, extensive erythrophagocytosis by macrophages may interfere with their antibacterial function and thereby predispose to infection. As a means of investigating this possibility, we evaluated the effects of erythrocyte ingestion on the Killing of Salmonella typhimurium by peritoneal… CONTINUE READING


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