Effect of ergot-alkaloid dihydroergosine on the immune reaction and plasma corticosterone in rats.

@article{mejkalJagar1993EffectOE,
  title={Effect of ergot-alkaloid dihydroergosine on the immune reaction and plasma corticosterone in rats.},
  author={Lidija {\vS}mejkal-Jagar and Nela Pivac and Milivoj Borani{\'c} and Danka Peri{\vc}i{\'c}},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={1993},
  volume={47 1},
  pages={
          33-6
        }
}
Ergot-alkaloid dihydroergosine, a potential antidepressive and anxiolytic drug, suppressed humoral and cellular immune reaction in rats, if given in a single injection (2-100 mg/kg) 1 hour after immunization. Plasma corticosterone levels were decreased upon assay of the immune response, 5 or 8 days following treatment. 

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ROLE OF ERGOT ALKALOIDS IN THE IMMUNE SYSTEM

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