Effect of epoprostenol on the thyroid gland: enlargement and secretion of thyroid hormone.

@article{Chadha2009EffectOE,
  title={Effect of epoprostenol on the thyroid gland: enlargement and secretion of thyroid hormone.},
  author={Chhavi Chadha and Marc R Pritzker and Cary N. Mariash},
  journal={Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists},
  year={2009},
  volume={15 2},
  pages={116-21}
}
OBJECTIVE To demonstrate the direct stimulation of thyroid tissue in the absence of thyroid-stimulating immunoglobulin after exposure to epoprostenol. METHODS Seronegative thyrotoxicosis, diffuse goiter, and homogeneous uptake on thyroid scintigraphy were noted in a patient with pulmonary arterial hypertension (PAH) being treated with intravenously administered epoprostenol (prostaglandin I2 or PGI2). More cases with similar characteristics were identified on review of the thyroid function in… CONTINUE READING