Effect of epithelial cell injury on anterior corneal oxygen flux.

  • L. Stephen Kwok
  • Published 1985 in
    American journal of optometry and physiological…


The aerobic response of epithelial metabolism to cellular injury or disease was studied with a three-layer model of the cornea. Nonclassical (Michaelis-Menten) respiratory kinetics were assumed, and predicted fluxes validated by reference to known estimates. The model indicates that epithelial oxygen flux is linearly related to epithelial oxygen consumption… (More)