Effect of epinephrine and potassium chloride on contraction and energy intermediates in rabbit thoracic aorta strips.

@article{Needleman1970EffectOE,
  title={Effect of epinephrine and potassium chloride on contraction and energy intermediates in rabbit thoracic aorta strips.},
  author={Philip Needleman and D J Blehm},
  journal={Life sciences. Pt. 1: Physiology and pharmacology},
  year={1970},
  volume={9 20},
  pages={
          1181-9
        }
}
Abstract Anoxic aortic strips incubated in the absence of glucose underwent a marked depletion of tissue metabolites. ATP and creatine-P fell to about 1 3 and the glycogen reserve was reduced to half. Epinephrine contraction could not be maintained and there was a further reduction in glycogen, ATP and creatine-P levels. The addition of glucose to anoxic epinephrine-treated strips enhanced contractility and increased ATP and creatine-P. A further increase in smooth muscle tension and… CONTINUE READING
BETA