Effect of enkephalins in the presence of the antibiotic bacitracin in the longitudinal muscle strip preparation from guinea-pig ileum

Abstract

The antibiotic bacitracin (5×10−5–4×10−4 M) increases the inhibition of the contractile response caused by both enkephalin release and direct application of Met-enkephalin 5×10−7 M in the longitudinal muscle strip preparation from guinea-pig ileum. This effect is attributed to an inhibition of enkephalin degrading peptidases by bacitracin. 
DOI: 10.1007/BF01948384

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