Effect of endogenous insulin release on fetal alanine concentration and uptake.


Insulin secretion in the fetus may be important in the modulation of selected fetal amino acid concentration and uptakes. To test this hypothesis we observed the changes in fetal alanine concentrations and uptake after tolbutamide-induced insulin release in the fetal lamb. The basal umbilical venous-arterial alanine difference was 29.1 +/- 4.2 mumoles/L… (More)