Effect of emodin on proliferation and differentiation of 3T3-L1 preadipocyte and FAS activity.

@article{Zhang2002EffectOE,
  title={Effect of emodin on proliferation and differentiation of 3T3-L1 preadipocyte and FAS activity.},
  author={Chongben Zhang and Lu Teng and Yan Shi and Junhua Jin and Youfang Xue and Kegang Shang and Jun Gu},
  journal={Chinese medical journal},
  year={2002},
  volume={115 7},
  pages={1035-8}
}
OBJECTIVE To study the effects of emodin on proliferation and differentiation of 3T3-L1 preadipocyte and the possible mechanism. METHODS Cell proliferation was determined by MTT spectrophotometry, cell differentiation was determined by Oil Red O staining,and fatty acid synthase (FAS) activity was determined by spectrophotometry. RESULTS Emodin promoted proliferation of 3T3-L1 preadipocyte at low concentration and inhibited the proliferation at high concentration in a dose-related manner. In… CONTINUE READING

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