Effect of eicosapentaenoic acid and docosahexaenoic acid on diabetic osteopenia.

@article{Yamada1995EffectOE,
  title={Effect of eicosapentaenoic acid and docosahexaenoic acid on diabetic osteopenia.},
  author={Yuya Yamada and Hisako Fushimi and Tae Inoue and Yutaka Matsuyama and Masakuni Kameyama and Takanori Minami and Yuko Okazaki and Yuichi Noguchi and Takeshi Kasama},
  journal={Diabetes research and clinical practice},
  year={1995},
  volume={30 1},
  pages={37-42}
}
To evaluate the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are polyunsaturated fatty acids, on diabetic osteopenia, we measured the bone fragility in streptozotocin-induced diabetic rats. The fragility of femur was increased in diabetic rats, which was prevented in part by EPA or DHA. Moreover, EPA prevented osteopenia even in diabetic rats fed a low zinc feed, which was a potent accelerator of diabetic osteopenia. Plasma alkaline phosphatase activity and… CONTINUE READING