Effect of eccentric exercise-induced muscle damage on the dynamics of muscle oxygenation and pulmonary oxygen uptake.

@article{Davies2008EffectOE,
  title={Effect of eccentric exercise-induced muscle damage on the dynamics of muscle oxygenation and pulmonary oxygen uptake.},
  author={Rosemary C. Davies and Roger Eston and David C. Poole and Ann V. Rowlands and Fred J. DiMenna and Daryl P. Wilkerson and Craig Twist and Andrew M. Jones},
  journal={Journal of applied physiology},
  year={2008},
  volume={105 5},
  pages={
          1413-21
        }
}
Unaccustomed eccentric exercise has a profound impact on muscle structure and function. However, it is not known whether associated microvascular dysfunction disrupts the matching of O2 delivery (Qo2) to O2 utilization (Vo2). Near-infrared spectroscopy (NIRS) was used to test the hypothesis that eccentric exercise-induced muscle damage would elevate the muscle Qo2:Vo2 ratio during severe-intensity exercise while preserving the speed of the Vo2 kinetics at exercise onset. Nine physically active… 
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It is demonstrated that exercise-induced muscle damage dissociates the [V dot] E response to incremental/ramp exercise from the blood lactate response, indicating that [Vdot] E may be controlled by additional or altered neurogenic stimuli following eccentric exercise.
Muscle damage slows oxygen uptake kinetics during moderate-intensity exercise performed at high pedal rate.
  • R. Molina, B. S. Denadai
  • Biology
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
  • 2011
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The slower VO₂ kinetics after muscle damage suggests that type II fibers are involved during transition to moderate-intensity exercise at high pedal cadence.
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Findings indicate that the augmented ventilatory response to cycle exercise following EIMD may be an important cue in informing effort perception during high- intensity exercise but not during moderate-intensity exercise.
Muscle damage alters the metabolic response to dynamic exercise in humans: a 31P-MRS study.
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The results indicate that alterations in phosphate metabolism, specifically the elevated [P(i)] at rest and throughout exercise, may contribute to the reduced exercise tolerance observed following EIMD.
Effect of exercise‐induced muscle damage on vascular function and skeletal muscle microvascular deoxygenation
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It is suggested that moderate eccentric muscle damage leads to impaired local, but not systemic, macrovascular dysfunction.
Effects of muscle-damaging exercise on physiological, metabolic, and perceptual responses during two modes of endurance exercise
Time-course of recovery of peak oxygen uptake after exercise-induced muscle damage
Changes in Skeletal Muscle Oxidative Capacity After a Trail Running Race.
PURPOSE to evaluate the effects of a trail-running race on muscle oxidative function by measuring pulmonary gas exchange variables and muscle fractional O2 extraction. METHODS Eighteen athletes…
Eccentric exercise slows in vivo microvascular reactivity during brief contractions in human skeletal muscle.
TLDR
Changes in microvascular regulation after eccentric exercise may impede rapid adjustments in muscle blood flow at exercise onset and during activities involving brief bursts of muscle activation, which may impair O2 delivery and contribute to reduced muscle function after eccentric Exercise.
The Effects of Exercise-Induced Muscle Damage on Cycling Time-Trial Performance
TLDR
Individuals using concurrent plyometric and endurance training programs to improve endurance performance should be aware of the acute impact of muscle-damaging exercise on subsequent cycling performance.
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