Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

Abstract

Methods In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition to… (More)

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@inproceedings{Shakur2017EffectOE, title={Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial}, author={Haleema Shakur and Ian Roberts and Bukola Fawole and Rizwana Chaudhri and M. El-Sheikh and Adesina L Akintan and Zahida Qureshi and Hussein Kidanto and Bellington Vwalika and Abdulfetah Abdulkadir and Saturday Job Etuk and Shehla Noor and Etienne Asonganyi and Zarko Alfirevi{\'c} and Danielle Beaumont and Carine Ronsmans and Sabaratnam Arulkumaran and Adrian M. Grant and Kaosar Afsana and Metin A. G{\"{u}lmezoglu and Beverley Hunt and Oladapo O Olayemi and Iain Chalmers and Pisake Lumbiganon and Gilda Piaggio and Tony Brady and Diana Elbourne and E. D. Balogun and T. Pepple and Danielle Prowse and Nigel Quashi and Lin Barneston and Collette Barrow and Lisa Cook and Lauren Frimley and D. J. Gilbert and Catherine Gilliam and Rob Jackson and Taemi Kawahara and Hakim Miah and Sergey V. Kostrov and Mar{\'i}a Ramos and Phil Edwards and Tom Godec and Sumaya Huque and Olujide Okunade and Olusade Adetayo and Aasia Kayani and Kiran Javaid and Chrstine Biryabarema and Robert Tchounzou and Mohan Chandra Regmi and Kastriot Dallaku and Mateus Sahani and Sayeba Akhter and Nicolas Y Meda and Anthony Kwame Dah and Olufemi Odekunle and Oluwabusola Monehin and Austin Ojo and Grace Akinbinu and Ifeoma Offiah and Ubong Bassey Akpan and Uduak Udofia and Useneno Okon and Ezukwa Omoronyia and Okpe James and Nike Bello and Blessed Adeyemi and Chris O. Aimakhu and Olufemi Akinsanya and Bamidele Adeleye and Oluwaseun Adeyemi and Kayode Oluwatosin and Abiodun P Aboyeji and Abiodun S. 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