Effect of early and delayed decompressive craniectomy on secondary brain damage after controlled cortical impact in mice.

@article{Zweckberger2006EffectOE,
  title={Effect of early and delayed decompressive craniectomy on secondary brain damage after controlled cortical impact in mice.},
  author={Klaus Zweckberger and Christian A. Eroes and Ricarda Zimmermann and Seong-Woong Kim and Doortje Engel and Nikolaus Plesnila},
  journal={Journal of neurotrauma},
  year={2006},
  volume={23 7},
  pages={1083-93}
}
The timing of decompressive craniectomy for the treatment of increased intracranial pressure (ICP) after traumatic brain injury (TBI) is a widely discussed clinical issue. Although we showed recently that early decompression is beneficial following experimental TBI, it remains unclear to what degree decompression craniectomy reduces secondary brain damage and if craniectomy is still beneficial when it is delayed by several hours as often inevitable during daily clinical practice. The aim of the… CONTINUE READING