Effect of dry fibrin sealant dressings versus gauze packing on blood loss in grade V liver injuries in resuscitated swine.

@article{Holcomb1999EffectOD,
  title={Effect of dry fibrin sealant dressings versus gauze packing on blood loss in grade V liver injuries in resuscitated swine.},
  author={John B. Holcomb and Anthony E. Pusateri and Richard A Harris and Norman C. Charles and R R Gomez and John G. P. Cole and Lawrence Beall and Vedat Bayer and M Macphee and John R Hess},
  journal={The Journal of trauma},
  year={1999},
  volume={46 1},
  pages={49-57}
}
BACKGROUND We conducted this study to determine whether the dry fibrin sealant dressing (DFSD) would stop bleeding from a grade V liver injury and to evaluate the effects of leaving the absorbable DFSD in survival animals. METHODS Twenty-four swine (40+/-3.0 kg) received a uniform grade V liver injury and were randomized to one of four 1-hour treatment groups: (1) gauze packing, (2) DFSD, (3) immunoglobulin G placebo dressing, and (4) no treatment. All animals were resuscitated with lactated… CONTINUE READING

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