Effect of drug resistance modulator, NO donor, on membrane structure and function of membrane-bound Ca2+-activated Mg2+-dependent ATPase

Abstract

Exogenous NO donor 3,3-bis-(nitroxymethyl)oxetane (NMO) was synthesized at the Institute for Problems of Chemical Physics (Russian Academy of Sciences). This compound was shown to inhibit Ca2+-ATPase isolated from normal muscular cells and tumor cells. Both hydrolytic and transport functions of the enzyme were inhibited under these conditions. These changes… (More)
DOI: 10.1007/s10517-008-0253-9

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@article{Rajewskaya2008EffectOD, title={Effect of drug resistance modulator, NO donor, on membrane structure and function of membrane-bound Ca2+-activated Mg2+-dependent ATPase}, author={T. A. Rajewskaya and S. A. Goncharova and Nadezhda Konovalova and Raisa A Kotelnikova and L. V. Tatyanenko}, journal={Bulletin of Experimental Biology and Medicine}, year={2008}, volume={146}, pages={200-202} }