Effect of drug-induced cytotoxicity on glucose uptake in Hodgkin's lymphoma cells.


BACKGROUND In Hodgkin's lymphoma, F-18-fluoro-deoxy-d-glucose positron emission tomography (FDG-PET) is used for staging and response evaluation after chemotherapy. However, drug-mediated downregulation of glucose uptake in viable Hodgkin's lymphoma cells might limit the use of FDG-PET. METHODS We analyzed the effect of etoposide on cell viability and… (More)