Effect of dopamine on ventilatory response to incremental exercise in man.

@article{Henson1992EffectOD,
  title={Effect of dopamine on ventilatory response to incremental exercise in man.},
  author={Lindsey C. Henson and Denham S. Ward and Brian Whipp},
  journal={Respiration physiology},
  year={1992},
  volume={89 2},
  pages={209-24}
}
We investigated whether dopamine, an inhibitory neuromodulator in the carotid body, would alter the ventilatory response typically associated with metabolic (lactic) acidosis during exercise. Six subjects performed incremental cycle ergometer exercise to exhaustion during infusions of dopamine (3 micrograms.kg-1.min-1) or saline. Ventilation and pulmonary gas exchange were computed breath-by-breath; arterialized venous blood was collected every 90 sec for measurement of lactate, potassium and… CONTINUE READING

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