Effect of donor age on the phosphorylation of the retinoblastoma gene product in cultured human keratinocytes.

Abstract

The retinoblastoma gene product (pRB) is a tumor suppressor protein. Recently, it has been shown that the phosphorylation of pRB is necessary for progression from G1 to S phase in a variety of cells. In a word, the phosphorylation of pRB accelerates cell growth. In this study, we examined the phosphorylation status of pRB in normal human keratinocytes… (More)

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Cite this paper

@article{Kobayashi1995EffectOD, title={Effect of donor age on the phosphorylation of the retinoblastoma gene product in cultured human keratinocytes.}, author={Tadao Kobayashi and Ken Hashimoto and Kazumasa Sudo and Seira Nishimoto and K Yoshikawa}, journal={Journal of dermatological science}, year={1995}, volume={9 1}, pages={59-63} }