Effect of domestic concentrations of nitrogen dioxide on airway responses to inhaled allergen in asthmatic patients

@article{Tunnicliffe1994EffectOD,
  title={Effect of domestic concentrations of nitrogen dioxide on airway responses to inhaled allergen in asthmatic patients},
  author={William Tunnicliffe and Peter Burge and Jon G. Ayres},
  journal={The Lancet},
  year={1994},
  volume={344},
  pages={1733-1736}
}
Nitrogen dioxide is a common indoor pollutant. In the light of suggestions that outdoor air pollution can harm people with asthma, we investigated the effect of 1 h exposures to domestic concentrations of nitrogen dioxide on the airway response to house-dust mite (HDM) allergen in ten patients with mild asthma. Each subject breathed air, 100 ppb nitrogen dioxide, or 400 ppb nitrogen dioxide for 1 h, in double-blind, random order, then immediately underwent a fixed-dose HDM challenge. Baseline… CONTINUE READING

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