Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: A quantitative analysis
@article{Bezzina2008EffectOD,
title={Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: A quantitative analysis},
author={G. Bezzina and S. Body and T. Cheung and C. Hampson and C. Bradshaw and E. Szabadi and I. Anderson and J. Deakin},
journal={Behavioural Brain Research},
year={2008},
volume={191},
pages={272 - 279}
}Previous experiments showed that destruction of the orbital prefrontal cortex (OPFC) or the nucleus accumbens core (AcbC) in rats altered choice between two delayed food reinforcers. Application of a quantitative model of inter-temporal choice suggested that lesions of either structure increased the delay-dependent degradation of reinforcer value (delay discounting); destruction of the OPFC (but not the AcbC) also increased the relative value of the larger reinforcer. This experiment examined… CONTINUE READING
41 Citations
Effects of lesions of the nucleus accumbens core on inter-temporal choice: Further observations with an adjusting-delay procedure
- Psychology, Medicine
- Behavioural Brain Research
- 2009
- 46
Choice between reinforcer delays versus choice between reinforcer magnitudes: Differential Fos expression in the orbital prefrontal cortex and nucleus accumbens core
- Psychology, Medicine
- Behavioural Brain Research
- 2010
- 34
Nucleus accumbens and delay discounting in rats: evidence from a new quantitative protocol for analysing inter-temporal choice
- Psychology, Medicine
- Psychopharmacology
- 2011
- 29
Quantitative analysis of the effect of lesions of the subthalamic nucleus on intertemporal choice: further evidence for enhancement of the incentive value of food reinforcers
- Psychology, Medicine
- Behavioural pharmacology
- 2009
- 18
Partial inactivation of nucleus accumbens core decreases delay discounting in rats without affecting sensitivity to delay or magnitude
- Psychology, Medicine
- Behavioural Brain Research
- 2014
- 18
Nucleus accumbens core and shell inactivation differentially affects impulsive behaviours in rats
- Psychology, Medicine
- Progress in Neuro-Psychopharmacology and Biological Psychiatry
- 2014
- 41
The Role of Ethanol and Neuroanatomical Regions in Sensitivity to Delay and Sensitivity to Magnitude of Reward
- Psychology
- 2014
- Highly Influenced
Effects of Intra-Accumbal Administration of Dopamine and Ionotropic Glutamate Receptor Drugs on Delay Discounting Performance in Rats
- Psychology, Medicine
- Behavioral neuroscience
- 2017
- 7
References
SHOWING 1-10 OF 50 REFERENCES
Effects of orbital prefrontal cortex dopamine depletion on inter-temporal choice: a quantitative analysis
- Psychology, Medicine
- Psychopharmacology
- 2004
- 110
Effects of lesions of the orbitofrontal cortex on sensitivity to delayed and probabilistic reinforcement
- Psychology, Medicine
- Psychopharmacology
- 2002
- 393
The effect of orbital prefrontal cortex lesions on performance on a progressive ratio schedule: implications for models of inter-temporal choice
- Psychology, Medicine
- Behavioural Brain Research
- 2005
- 71
Effects of quinolinic acid-induced lesions of the orbital prefrontal cortex on inter-temporal choice: a quantitative analysis
- Psychology, Medicine
- Psychopharmacology
- 2002
- 117
Double dissociation of the effects of selective nucleus accumbens core and shell lesions on impulsive‐choice behaviour and salience learning in rats
- Psychology, Medicine
- The European journal of neuroscience
- 2005
- 166
- PDF
Contrasting Roles of Basolateral Amygdala and Orbitofrontal Cortex in Impulsive Choice
- Psychology, Medicine
- The Journal of Neuroscience
- 2004
- 546
- PDF
Effects of excitotoxic lesions of the rat ventral striatum on the perception of reward cost
- Psychology, Medicine
- Experimental Brain Research
- 1998
- 61
Effects of quinolinic acid-induced lesions of the nucleus accumbens core on inter-temporal choice: a quantitative analysis
- Psychology, Medicine
- Psychopharmacology
- 2007
- 77
Orbitofrontal Cortex and Representation of Incentive Value in Associative Learning
- Psychology, Medicine
- The Journal of Neuroscience
- 1999
- 510
- PDF
Role of the orbital prefrontal cortex in choice between delayed and uncertain reinforcers: a quantitative analysis
- Psychology, Medicine
- Behavioural Processes
- 2003
- 60