Effect of diphosphonate on the prevention of X-radiation-induced inhibition of bone formation in rats.

@article{Ubios1986EffectOD,
  title={Effect of diphosphonate on the prevention of X-radiation-induced inhibition of bone formation in rats.},
  author={Angela Matilde Ubios and Mar{\'i}a Beatriz Guglielmotti and R{\'o}mulo Luis Cabrini},
  journal={Journal of oral pathology},
  year={1986},
  volume={15 9},
  pages={
          500-5
        }
}
A histologic and histometric study of the effect of EHDP (ethane-1-hydroxy-1,1-diphosphonate) on the alveolar wound healing of irradiated animals is presented. This drug was selected based on its osteosclerotic effect when applied at low doses. The three left mandibular molars of 80 male Wistar rats were extracted. The rats were grouped into 4 sets of 20 rats each. Group I received no further treatment; Group II received daily intraperitoneal injections of EHDP (7.5 mg/Kg of body weight during… CONTINUE READING