Effect of dimethyl sulfoxide on the function and structure of the intact and ischemic canine ileum.


The action of dimethyl sulfoxide (DMSO) was investigated employing an experimental model of intestinal perfusion in vivo of isolated loops of dog ileum before, during, and following 1-h ischemia. DMSO was administered either into the intestinal lumen or by a continuous injection via a branch of the artery supplying the experimental loop. In the intact… (More)


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