Effect of different lipids and surfactants on formulation of solid lipid nanoparticles incorporating tamoxifen citrate

@inproceedings{Upadhyay2012EffectOD,
  title={Effect of different lipids and surfactants on formulation of solid lipid nanoparticles incorporating tamoxifen citrate},
  author={Shyam Upadhyay and J. K. Patel and Vishnu A. Patel and A. K. Saluja},
  booktitle={Journal of pharmacy & bioallied sciences},
  year={2012}
}
Tamoxifen Citrate (TC) is an estrogen receptor antagonist and drug of choice for hormone sensitive breast cancer. Solid Lipid Nanoparticles loaded with TC were prepared by High Shear Homogenization followed by Ultrasonication. The aim of the present work is to study the effect of four different Solid Lipids and three Surfactants on Formulation and Stability of SLN. They were characterized for Particle size, Polydispersity Index and Zeta Potential by Zetasizer Nano. SLN prepared by Solid Lipid… CONTINUE READING

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