Effect of different extracts from the Brazilian Atlantic Forest on the Pdr5p ATPase activity

@inproceedings{Rangel2008EffectOD,
  title={Effect of different extracts from the Brazilian Atlantic Forest on the Pdr5p ATPase activity},
  author={Luciana Pereira Rangel and Lisandra Ferreira de Abreu and Ana Rodrigues de Andrade and Suzana Guimar{\~a}es Leit{\~a}o and Gilda Guimar{\~a}es Leit{\~a}o and A Ferreira-Pereira},
  year={2008}
}
In the current study, we tested the effect of 27 plant extracts and fractions from different botanical families on the activity of Pdr5p from yeast plasma membrane, responsible for the multidrug resistance phenotype in yeast cells. Some of the extracts were able to produce a good inhibition in the fi xed concentration (200 g/mL) and were selected for a deeper investigation. Dose-response curves were obtained for the crude ethanol extracts of Bathysa australis (A. St.Hill.) Benth. & Hook f… CONTINUE READING

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