Effect of different barriers of oxidized regenerated cellulose (ORC) on cecal and sidewall adhesions in the presence and absence of bleeding.

@article{Wiseman1999EffectOD,
  title={Effect of different barriers of oxidized regenerated cellulose (ORC) on cecal and sidewall adhesions in the presence and absence of bleeding.},
  author={David M Wiseman and L Gottlick-Iarkowski and Lucas Kamp},
  journal={Journal of investigative surgery : the official journal of the Academy of Surgical Research},
  year={1999},
  volume={12 3},
  pages={141-6}
}
Adhesion formation after bowel surgery is a significant problem. The objective of this study was to evaluate two adhesion barriers composed of oxidized regenerated cellulose (ORC) in a model of bowel surgery, with and without bleeding. Ceca of female New Zealand White rabbits were abraded with gauze and a 3 x 5 cm patch of peritoneum and underlying muscle was excised from the right sidewall. Animals were randomized to receive no treatment, INTERCEED Barrier (Ethicon, Inc.), or neutralized… CONTINUE READING