Effect of dietary restriction and N-acetylcysteine supplementation on intestinal mucosa and liver mitochondrial redox status and function in aged rats.

Abstract

The age-related changes of glutathione (GSH) levels and the effect of hypocaloric regimen and N-acetylcysteine (NAC) supplementation were investigated in intestinal mucosa and liver mitochondria of 28 months rats. Old rats exhibited lower proteins, GSH and protein sulphydrils (PSH) concentrations, higher GSH-peroxidase (GSH-Px) activity and protein carbonyl… (More)

Topics

Cite this paper

@article{Grattagliano2004EffectOD, title={Effect of dietary restriction and N-acetylcysteine supplementation on intestinal mucosa and liver mitochondrial redox status and function in aged rats.}, author={Ignazio Grattagliano and Piero Portincasa and Tiziana Cocco and Antonio Moschetta and Marco Di Paola and Vincenzo Ostilio Palmieri and Giuseppe Palasciano}, journal={Experimental gerontology}, year={2004}, volume={39 9}, pages={1323-32} }