• DOI:10.2131/JTS.18.103
Corpus ID: 40573555

Effect of dietary protein and sulfur-containing amino acids on urinary metabolites in rats injected with chlorobenzene.

@article{Goto1993EffectOD,
  title={Effect of dietary protein and sulfur-containing amino acids on urinary metabolites in rats injected with chlorobenzene.},
  author={H. Goto and M. Yoshida and Naoki Nakazono},
  journal={The Journal of toxicological sciences},
  year={1993},
  volume={18 2},
  pages={
          103-9
        }
}

H. Goto, M. Yoshida, Naoki Nakazono

Published 1993

Chemistry, Medicine

The Journal of toxicological sciences

Rats were fed for 10 days a 10 or 20% casein diet, or the diets with 0.3% DL-methionine or L-cystine. Rats fed the 20% casein exceeded those fed the 10% casein in growth, hepatic glutathione (GSH) levels, and microsomal drug-metabolizing activities including cytochrome P-450, aminopyrine N-demethylase, and aniline hydroxylase. Supplement with methionine or cystine had significantly elevated hepatic GSH, regardless of the casein content. After the feeding, rats were intraperitoneally injected… CONTINUE READING

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