Corpus ID: 13658039

Effect of dietary lipids on inotropic responses of isolated rat left atrium: attenuation of maximal responses by an unsaturated fat diet.

@article{Wince1987EffectOD,
  title={Effect of dietary lipids on inotropic responses of isolated rat left atrium: attenuation of maximal responses by an unsaturated fat diet.},
  author={L. C. Wince and L. E. Hugman and W. Chen and R. Robbins and G. M. Brenner},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1987},
  volume={241 3},
  pages={
          838-45
        }
}
The effect of varying the dietary fatty acid composition on inotropic responses to various pharmacological agents was investigated in isolated rat left atrium. Pregnant rats were fed either semisynthetic diets supplemented with coconut oil (saturated fatty acids), sunflower oil (unsaturated) or Purina Rodent Chow. Newborns were exposed through the maternal milk and later fed the same diets throughout adulthood. Sunflower oil caused a significant decrease in the maximal response of adult atria… Expand
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