Effect of dietary GLA+/−tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts

@article{Kenny2001EffectOD,
  title={Effect of dietary GLA+/−tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts},
  author={F. S. Kenny and J. Gee and R. Nicholson and I. Ellis and T. Morris and S. Watson and R. Bryce and J. Robertson},
  journal={International Journal of Cancer},
  year={2001},
  volume={92}
}
Gamma linolenic acid (GLA) possesses a number of selective anti‐tumour properties including modulation of steroid receptor structure and function. We have investigated the effect of dietary GLA on the growth, oestrogen receptor (ER) expression and fatty acid profile of ER+ve human breast cancer xenografts. Experimental diets A, B, C, D were commenced after subcutaneous implantation of 40 female nude mice with the MCF‐7 B1M cell line (Group A = control diet: B = control diet + GLA supplement: C… Expand
In‐vitro transcutaneous delivery of tamoxifen and γ‐linolenic acid from borage oil containing ethanol and 1,8‐cineole
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