Effect of diesel exhaust particulate (DEP) on immune responses: contributions of particulate versus organic soluble components.

@article{Siegel2004EffectOD,
  title={Effect of diesel exhaust particulate (DEP) on immune responses: contributions of particulate versus organic soluble components.},
  author={Paul D. Siegel and Rajiv Kumar Saxena and Queen B. Saxena and Joseph K. H. Ma and Jane Y. C. Ma and Xuejun Yin and Vincent Castranova and Nabil H Al-Humadi and Daniel M Lewis},
  journal={Journal of toxicology and environmental health. Part A},
  year={2004},
  volume={67 3},
  pages={221-31}
}
The effect of diesel exhaust particulate (DEP) exposure on innate, cellular and humoral pulmonary immunity was studied using high-dose, acute-exposure rat, mouse, and cell culture models. DEP consists of a complex mixture of petrochemical-derived organics adsorbed onto elemental carbon particles. DEP is a major component of particulate urban air pollution and a health concern in both urban and occupational environments. The alveolar macrophage is considered a key cellular component in pulmonary… CONTINUE READING

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