Effect of dienogest-containing oral contraceptives on lipid metabolism.

  title={Effect of dienogest-containing oral contraceptives on lipid metabolism.},
  author={Inka Wiegratz and Jin Hee Lee and Eric Kutschera and Horst H. Bauer and C von Hayn and Claudia B Moore and Uwe Mellinger and Ulrich H Winkler and Werner Gross and Herbert Kuhl},
  volume={65 3},
In a double-blind, controlled, randomized, four-arm, bicentric clinical study, the effect of four oral contraceptives (OCs) on lipid metabolism was investigated. Four groups composed of 25 volunteers each (mean age 26.1 +/- 4.5 years; body mass index 21.9 +/- 2.8 kg/m(2)) were treated for six cycles with monophasic combinations containing 21 tablets with either 30 microg ethinyl estradiol (EE) + 2 mg dienogest (DNG) (30 EE/DNG), 20 microg EE + 2 mg DNG (20 EE/DNG), 10 microg EE + 2 mg estradiol… CONTINUE READING


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