Effect of diabetes on alteration of metabolism in cardiac myocytes: therapeutic implications.

Abstract

Diabetic cardiomyopathy is a distinct entity in humans. It leads to ventricular dysfunction independent of and additive to coronary artery disease and hypertension. Clinical and experimental studies have pointed to the role of metabolic derangements in the development of diabetic cardiomyopathy. Altered insulin signaling in diabetes leads to decreased… (More)
DOI: 10.1089/dia.2011.0120

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