Effect of dexamethasone or synthetic ACTH administration on endogenous ACTH concentrations in healthy dogs.

@article{Bugbee2013EffectOD,
  title={Effect of dexamethasone or synthetic ACTH administration on endogenous ACTH concentrations in healthy dogs.},
  author={Andrew Bugbee and Jo R Smith and C. R. Ward},
  journal={American journal of veterinary research},
  year={2013},
  volume={74 11},
  pages={1415-20}
}
OBJECTIVE To determine the effects of dexamethasone or synthetic ACTH administration on endogenous ACTH concentrations in healthy dogs. ANIMALS 10 healthy neutered dogs. PROCEDURES Each dog received dexamethasone (0.01 mg/kg), synthetic ACTH (5 μg/kg), or saline (0.9% NaCl) solution (0.5 mL) IV at intervals of ≥ 30 days. Plasma endogenous ACTH concentrations were measured before (baseline; time 0) and 1, 8, 12, and 24 hours after drug administration; serum cortisol concentrations were… CONTINUE READING
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