Effect of dexamethasone on peripheral blood leukocyte immune response in bile-pancreatic duct obstruction-induced acute pancreatitis

@article{Ramudo2010EffectOD,
  title={Effect of dexamethasone on peripheral blood leukocyte immune response in bile-pancreatic duct obstruction-induced acute pancreatitis},
  author={Laura Ramudo and Sara Yubero and Manuel Antonio Manso and Javier S{\'a}nchez Recio and Eduardo Weruaga and Isabel de Dios},
  journal={Steroids},
  year={2010},
  volume={75},
  pages={362-367}
}
Our aim was to analyze the effects of dexamethasone (Dx) (1mg/kg), prophylactically or therapeutically administered, on the inflammatory response triggered by peripheral blood leukocytes during acute pancreatitis (AP) induced in rats by bile-pancreatic duct obstruction (BPDO) and their consequences in the progress of the disease. Flow cytometry was used to analyze the distribution of the major leukocyte populations, the CD45 expression and the activated state of monocytes as reflected by the… CONTINUE READING
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