Effect of dexamethasone and testosterone treatment on the regulation of insulin-degrading enzyme and cellular changes in ventral rat prostate after castration.

@article{Vieira2011EffectOD,
  title={Effect of dexamethasone and testosterone treatment on the regulation of insulin-degrading enzyme and cellular changes in ventral rat prostate after castration.},
  author={Juliany S B C{\'e}sar Vieira and Karina Lidianne Alc{\^a}ntara Saraiva and Maria do Carmo Lacerda Barbosa and Regina C C Porto and Juan Carlos Cresto and Christina Alves Peixoto and Maria In{\^e}s Wanderley and Daniel Pedro Udrisar},
  journal={International journal of experimental pathology},
  year={2011},
  volume={92 4},
  pages={272-80}
}
Insulin-degrading enzyme (IDE) has been shown to enhance the binding of androgen and glucocorticoid receptors to DNA in the nuclear compartment. Glucocorticoids cause hyperglycaemia, peripheral resistance to insulin and compensatory hyperinsulinaemia. The aim of the present study was to investigate the effect of dexamethasone (D), testosterone (T) and… CONTINUE READING