Effect of development and aging on the response of canine lymphocytes to phytohemagglutinin.

@article{Gerber1974EffectOD,
  title={Effect of development and aging on the response of canine lymphocytes to phytohemagglutinin.},
  author={Jean-Pierre Gerber and Abigail Leigh Brown},
  journal={Infection and immunity},
  year={1974},
  volume={10 4},
  pages={695-9}
}
The stage of development and age were found to effect the responsiveness of dog T-lymphocytes to phytohemagglutinin. T-lymphocytes from beagles 0 to 4 weeks of age showed significantly less response to phytohemagglutinin (P < 0.001) than T-lymphocytes from these same dogs at 6 to 12 weeks of age. Peak response to phytohemagglutinin occurred between 6 weeks to 6 months of age, after which there was a significant correlation (P < 0.02) between increase in age and decrease in phytohemagglutinin… CONTINUE READING