Effect of destruction of the 5-hydroxytryptaminergic pathways on the acquisition of temporal discrimination and memory for duration in a delayed conditional discrimination task

@article{Alzahrani1996EffectOD,
  title={Effect of destruction of the 5-hydroxytryptaminergic pathways on the acquisition of temporal discrimination and memory for duration in a delayed conditional discrimination task},
  author={Saeed Al-zahrani and M. -Y. Ho and D. N. Vel{\'a}zquez Mart{\'i}nez and M. L{\'o}pez Cabrera and Christopher M. Bradshaw and Elem{\'e}r Szabadi},
  journal={Psychopharmacology},
  year={1996},
  volume={123},
  pages={103-110}
}
This experiment examined the effect of destruction of the ascending 5-hydroxytryptaminergic (5HTergic) pathways on the acquistion of a temporal discrimination and on memory for duration, using a delayed conditional discrimination task. In phase I, rats that had received injections of 5,7-dihydroxytryptamine into the dorsal and median raphe nuclei, and shamlesioned control rats, were trained in a series of discrete trials to press lever A following a 2-s presentation of a light stimulus, and… CONTINUE READING

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The levels of 5HT and 5-hydroxyindoleacetic acid were reduced in the brains of the lesioned rats , but the levels of noradrenaline and dopamine were not altered .
The levels of 5HT and 5-hydroxyindoleacetic acid were reduced in the brains of the lesioned rats , but the levels of noradrenaline and dopamine were not altered .
DopamineSibling in is aNorepinephrine
The levels of 5HT and 5-hydroxyindoleacetic acid were reduced in the brains of the lesioned rats , but the levels of noradrenaline and dopamine were not altered .
NorepinephrineSibling in is aDopamine
The levels of 5HT and 5-hydroxyindoleacetic acid were reduced in the brains of the lesioned rats , but the levels of noradrenaline and dopamine were not altered .
The levels of 5HT and 5-hydroxyindoleacetic acid were reduced in the brains of the lesioned rats , but the levels of noradrenaline and dopamine were not altered .
The levels of 5HT and 5-hydroxyindoleacetic acid were reduced in the brains of the lesioned rats , but the levels of noradrenaline and dopamine were not altered .
The levels of 5HT and 5-hydroxyindoleacetic acid were reduced in the brains of the lesioned rats , but the levels of noradrenaline and dopamine were not altered .
The levels of 5HT and 5-hydroxyindoleacetic acid were reduced in the brains of the lesioned rats , but the levels of noradrenaline and dopamine were not altered .
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